Research in Malaysia

Recent research output from Malaysia (via PubMed). Updated automatically.

Related Articles

Quercetin interferes with the fluid volume and receptivity development of the uterus in rats during the peri-implantation period.

Reprod Toxicol. 2017 Apr 18;:

Authors: Shahzad H, Giribabu N, Karim K, Kassim N, Muniandy S, Kumar KE, Salleh N

Abstract
HYPOTHESIS: quercetin could induce changes to the fluid volume and receptivity development of the uterus during peri-implantation period.
METHODS: Female rats were treated with quercetin (10, 25 and 50mg/kg/day) subcutaneously beginning from day-1 pregnancy. Uterus was harvested at day-4 (following three days quercetin treatment) for morphological, ultra-structural, protein and mRNA expressional changes and plasma sex-steroid levels analyses. In another cohort of rats, implantation rate was determined at day-6 (following five days quercetin treatment).
RESULTS: Administration of 50mg/kg/day quercetin causes increased in uterine fluid volume and CFTR expression but decreased in γ-ENaC, AQP-5, AQP-9 claudin-4, occludin, E-cadherin, integrin αnβЗ, FGF, Ihh and Msx-1expression in the uterus. Pinopodes were poorly develop, tight junctions appear less complex and implantation rate decreased. Serum estradiol levels increased but serum progesterone levels decreased.
CONCLUSIONS: Interference in the fluid volume and receptivity development of the uterus during peri-implantation period by quercetin could adversely affect embryo implantation.

PMID: 28431985 [PubMed - as supplied by publisher]

Related Articles

Trends in Geriatrics-Related Translational Research and Funding in the "Big 4" Medical Journals.

J Am Med Dir Assoc. 2017 Apr 18;:

Authors: Ch'ng ASH, Yong KTW, Ng DWH, Heyzer L, Lim WS

PMID: 28431910 [PubMed - as supplied by publisher]

Related Articles

Pneumatic jigging: Influence of operating parameters on separation efficiency of solid waste materials.

Waste Manag Res. 2017 Apr 01;:734242X17697815

Authors: Abd Aziz MA, Md Isa K, Ab Rashid R

Abstract
This article aims to provide insights into the factors that contribute to the separation efficiency of solid particles. In this study, a pneumatic jigging technique was used to assess the separation of solid waste materials that consisted of copper, glass and rubber insulator. Several initial experiments were carried out to evaluate the strengths and limitations of the technique. It is found that despite some limitations of the technique, all the samples prepared for the experiments were successfully separated. The follow-up experiments were then carried out to further assess the separation of copper wire and rubber insulator. The effects of air flow and pulse rates on the separation process were examined. The data for these follow-up experiments were analysed using a sink float analysis technique. The analysis shows that the air flow rate was very important in determining the separation efficiency. However, the separation efficiency may be influenced by the type of materials used.

PMID: 28431479 [PubMed - as supplied by publisher]

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